I have seen so many of these and own so many also that it's not hard to tell a Misaligned Strike. Thick at 10 o'clock and Thin at 4 o'clock is a better area description @ken454
EASY! He is probably referring to the distance (Thickness - IMO a poor choice of words) between the edge of the coin and its design on either side. IMO, it is not enough to be called a misaligned die at a TPGS. I is definitely slightly off though. The die wear ridge on the left is more significant/interesting to me; yet the coin should not be worth a whole lot to most collectors..
Can't really tell about the doubled S due to the low photo quality. If you can take a closeup of the mint mark in a well lit room without flash, we might be able to give a better opinion.