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<p>[QUOTE="mrbrklyn, post: 553955, member: 4381"]Actually the rDNA therapies and the ability to grow them in broths is an exciting breakthrough and it is going to have major impact in the near future. You were telling me about them before and you opened up my eyes to how this is currently developing. There are catches though. I went to San Fransisco last year for a weeks worth of meetings and work shops on recombinant anti-bodies and biological developments. The trouble they run into, and this is critical for dosage delivery systems, is that these very biological active compounds are also highly antigenic by design. They are functioning right there at the level of immunological activation and they already had one very very bad clinical trial. </p><p><br /></p><p>Our technology might just not be there yet because to avoid this kind of problem within realistic and practical levels of safety, it might be necessary to build a cocktail mapped directly to the immunological conditions of the patients and rDNA fermentation might go a long way towards that. But there are a lot of hurdles to leap over, not the least of which is that a normal drug is tested on 500 patients in primary clinical trials, and thousands of patients in secondary trials before being released. Here what we are proposing is that each batch is a new and different delivery system going to the patient without ANY trials, and once those slow releasing intracellular mediators get released into the blood stream, all a MD can do is supportive medicine and watch the results with horror.</p><p><br /></p><p>Ruben[/QUOTE]</p><p><br /></p>
[QUOTE="mrbrklyn, post: 553955, member: 4381"]Actually the rDNA therapies and the ability to grow them in broths is an exciting breakthrough and it is going to have major impact in the near future. You were telling me about them before and you opened up my eyes to how this is currently developing. There are catches though. I went to San Fransisco last year for a weeks worth of meetings and work shops on recombinant anti-bodies and biological developments. The trouble they run into, and this is critical for dosage delivery systems, is that these very biological active compounds are also highly antigenic by design. They are functioning right there at the level of immunological activation and they already had one very very bad clinical trial. Our technology might just not be there yet because to avoid this kind of problem within realistic and practical levels of safety, it might be necessary to build a cocktail mapped directly to the immunological conditions of the patients and rDNA fermentation might go a long way towards that. But there are a lot of hurdles to leap over, not the least of which is that a normal drug is tested on 500 patients in primary clinical trials, and thousands of patients in secondary trials before being released. Here what we are proposing is that each batch is a new and different delivery system going to the patient without ANY trials, and once those slow releasing intracellular mediators get released into the blood stream, all a MD can do is supportive medicine and watch the results with horror. Ruben[/QUOTE]
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