Even if the numerous scratches I see are unrelated to the design absence, adroit individuals can remove the design without leaving any signs of abrasion. Why don't you weigh the coin? If metal has been removed, it should leave the coin slightly underweight.
Ok, I weighed the coin. I also weighed 49 other coins and this is what I found. The coin in question as a weak strike/die adjustment/PMD weighed 4.92 grams. The average of all the nickels was 5. 0134. The heaviest nickel weighed a whopping 5.12 grams. My coin, that started this, was the lightest coin and was 1.84% lighter than the average weight. The heaviest coin was 2.14% higher than the average. It looks completely normal. The other 49 coins were picked at total random from my change jar. The fact that my coin looks like it was ground down and is the lightest of all the nickels tells me that the most likely cause is PMD. I accept it now but it still baffles me. Thanks for all the input. And thank you Mike Diamond for so much time out of your busy life and patience with a newbie.
Although 4.92 grams still falls within the normal range of variation for nickels, the fact that this weight is found in association with a missing central design adds to the preponderance of evidence in favor of alteration.