Message:

<p>[QUOTE=&quot;mrbrklyn, post: 561665, member: 4381&quot;]then as a chemist you need to rethink it and this often happens when chemists come to the pharmacy industry.&nbsp; They forget they basic toxicology.&nbsp; Anything with an acetone group is a potential carcinogen and dangerous.&nbsp; As for acetone not being lipophilic, with all do respect, first that is not what I said.&nbsp; I said its lipophilic properties allow for passing through skin tissue.&nbsp; That is a 100% correct statement and I&#039;ve had to knock down repeaed attempts by student chemists to use Acetone in drug delivery systems.&nbsp; A heavily lipophilic substance doesn&#039;t pass readily and a highly polar substance doesn&#039;t either.&nbsp; But a substance like Acetone and Alcohol gets very rapid systemic absorption through the skins lipoprotein cell membrane.&nbsp; And ALL organic solvents have to have about the same balance of Pk associativity and Lipophilic properties, roughly 2/3rds of water, or they don&#039;t dissolve the highly lipophilic organic material.&nbsp; And this is especially true of long chained polymers such as paint where the weak lipophilic bounds collectively form the free energy necessary for the adhesive properties of the surface to surface partition between the chemical and the substrate it is glued to.</p><p><br /></p><p>So what do we want to do next?&nbsp; Should we take a mouse and put it in a acetone bath for a month and see if it develops legions, when the mouse doesn&#039;t die of liver poisoning first?&nbsp; Because the Pharmacy industry has done that already and that is exactly the result.</p><p><br /></p><p>Ruben[/QUOTE]</p><p><br /></p>

Your name or email address:

Do you already have an account?

• No, create an account now.
• Yes, my password is:
• Forgot your password?

Stay logged in