I would think so. I’ve seen coins from a building fire. Some of the coins were melted, others were fused together and some even had pieces of wood permanently attached to the coin.
Your (excellent as usual) close-ups make it look like the "patch" is acid-damaged, and since the pattern's uniform across the field and device, I don't think it could be a mint issue. It doesn't look like what would be left behind by a detached lamination, at least to me. "Fire" and "corrosion" seem like two different things, but they can be pretty similar at a chemical level. Fire can corrode before it melts metal.
