Wow. Really nice box for sure buddy! Damaged or not if you pull a 50 out of circulation you saved it from further damage!
That 1941 S Large S is probably the most valuable find in the box. The Large S is not a common find, so it's value is proportionate to it's condition and a weighted factor. Perhaps 10x a Small S variety. See this write up from a while back - VARIETY: 1941-S Large "S" Jefferson Nickel FS-501 | Coin Talk