I pulled this nickle out of a roll search. I thought the rim looked a little un even. Is this just wear or a die strike issue?
It depends what the other side looks like. It might be struck just a tiny, tiny bit off center, or it could be a misaligned die strike. In either case, it has nothing to do with wear.
Within normal striking parameters. When the devices are cut by the edge is when it's probably a keeper.