Not sure if it happened PMD or at mint. Would it cause doubling if it happened at the mint is my second question.
I'm not sure what it is but that is nothing to do with partial missing clad. Some kind of damage IMHO.
Looks like a chemical was on the coin on both sides (same area). The green verdigris might be a sign of it too. Not a clad layer defect, imo.
On the photo I showed, if the clad had been removed post strike, the details on the copper side would be mushy. But, if the coin was struck with the clad already missing, then you can see the details are much sharper.