The signatures will change, but probably the series will remain the same until the 2020 portrait revamp.
Under the current rules you would get a new series if both signatures change. With a new incoming administration there is a fairly good chance we could get both a new Sec Treas and Treasurer. Even if they did and they do create a new Series 2017 there would be a good chance that it wouldn't be released until sometime next year. It takes some time to create the new printing plates and they don't stop using the old ones until they wear out.